Managing Side Effects With Isotretinoin

While isotretinoin is an excellent medication for acne, it can result in side effects. The more severe side effects include the potential to cause severe birth defects and changes in cholesterol and liver enzymes (which is why it’s essential not to get pregnant while on the medication and to have your doctor perform regular blood tests). However, the most common thing patients notice is that it can also be very drying, often a new problem for acne patients.

Many products that patients may be using already to treat acne can further irritate the skin. Discontinue products that include drying or irritating ingredients, including benzoyl peroxide, salicylic acid, glycolic acid, AHAs/BHAs, toners, and retinoids

Here is how to manage the common dry areas:

Skin:

Make sure to steer clear of harsh and drying cleansers that strip the skin of its natural oils.

I recommend:

CeraVe® Hydrating Cleanser

Unscented Vanicream® Gentle Facial Cleanser

La Roche-Posay® Toleriane Hydrating Gentle Cleanser

Apply sensitive skin moisturizers to dry skin at least two times a day.

I would recommend:

You should apply a non-comedogenic sunscreen (SPF 30) in the morning and reapply every 2 hours when outside.

I would recommend:

Eyes

Use saline eye drops or artificial tears without preservatives.

Lips

Apply petrolatum-based lip balms routinely. Avoid anything “medicated.”

I recommend Vaseline, Aquaphor, and Cerave Healing Ointment

Nose

Use the saline nasal spray and a small amount of petrolatum jelly into the nose, during the day and at bedtime.

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